Plasma active and inactive renin in patients with diabetes mellitus.

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Plasma inactive renin in patients with diabetes mellitus: effects of standing and the relation to serum protease inhibitor.

In order to investigate the mechanisms of increased plasma inactive renin in diabetics with microvascular complications, changes in active and inactive renin with the progress of diabetes mellitus were studied, and effects of standing on inactive renin release and the relationship between plasma inactive renin and serum trypsin or protease inhibitors wee also studied. Inactive renin increased w...

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Plasma renin activity in diabetes mellitus.

1. The plasma renin activity (PRA) was measured in 76 diabetic patients who were attending an outpatients clinic. Of these patients 16 had untreated hypertension and 28 had diabetic complications, which ranged from microaneurysms to renal failure and blindness. 2. Compared with age- and sex-matched normotensive control subjects, both normotensive and hypertensive diabetic patients had significa...

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PLASMA DEHYDROASCORBIC ACID LEVELS IN IRANIAN SUBJECTS WITH DIABETES MELLITUS

Several reports concerning high plasma dehydroascorbic acid (DHAsA) levels in diabetics have been published and from these reports, suggestions that monitoring of DHAsA levels in those persons with a predisposition to diabetes mellitus would be of value. However, conflicting reports have also appeared which do not confirm high levels of DHAsA in diabetic subjects when compared to controls....

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Pathophysiological significance of plasma total renin and prorenin in patients with diabetes mellitus.

To seek the pathophysiologic significance of measuring the concentration of total renin instead of prorenin, we determined the plasma total renin concentration by immunoradiometric assay and correlated the results with various clinical features and laboratory parameters of diabetic complication in 108 patients with diabetes mellitus. The plasma prorenin concentration was estimated as the differ...

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Plasma renin and prorenin and renin gene variation in patients with insulin-dependent diabetes mellitus and nephropathy.

BACKGROUND The most striking abnormality in the renin angiotensin system in diabetic nephropathy (DN) is increased plasma prorenin. Renin is thought to be low or normal in DN. In spite of altered (pro)renin regulation the renin gene has not been studied for contribution to the development of DN. METHODS We studied plasma renin, prorenin, and four polymorphic markers of the renin gene in 199 p...

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ژورنال

عنوان ژورنال: Endocrinologia Japonica

سال: 1980

ISSN: 0013-7219,2185-6370

DOI: 10.1507/endocrj1954.27.65